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Glucagon-like peptide-1 receptor (GLP-1R) is a G protein-coupled receptor widely expressed on the surface of a wide range of cells in the human body, including pancreatic islet , and cells, as well as multiple tissues such as the intestines, stomach, lungs, heart, kidneys, and central nervous system

the effects of AICAR on the intracellular lipid deposition were reversed by PARP-1 (Figure 4D)

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However, some patients taking this GLP-1 receptor agonist have reported noticing urinary odour changes during treatment