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Effects of low-dose, controlled-release phentermine plus topiramate combination

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Because the peptide potently and aggressively stimulates angiogenesis via the VEGF/VEGFR2 pathways, there is a theoretical, but highly biologically plausible, risk that BPC-157 could inadvertently supply massive new blood flow to existing, undiagnosed malignant tumors, thereby acting as a catalyst for rapid cancer metastasis

Thats why titrating the dose through the treatment is vital.

However, translation of these findings to adult human obesity remains constrained by fundamental physiological differences, including limited brown adipose tissue mass and reduced thermogenic capacity