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Common gastrointestinal side effects occur in many patients and include: Nausea (most common, typically improving after 4-8 weeks) Vomiting Diarrhea Constipation Abdominal pain or discomfort Decreased appetite These effects result from the drugs' mechanism of actionslowing gastric emptying and affecting gut motilityrather than indicating tissue damage or malignancy
Symptoms of long-term chromium deficiency include severely impaired glucose tolerance, weight loss, peripheral neuropathy and confusion
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