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The documented label and trial protocol does not use a single fixed dose

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Ironically, a side effect of excessive anticholinesterase treatment is excessive weakness or cholinergic crisis due to excessive stimulation of nicotinic receptors in the muscle end-plate region, resulting in a transient phase of uncontrolled muscle fasciculations due to sustained depolarization, followed by the development of receptor desensitization and a flaccid paralysis

"I'm concerned that we're responding to a market-induced demand rather than a decision based in solid science," Dr

Surg Clin N Am 64:721733 Cerovecki T, Bojanic I, Brcic L, Radic B, Vukoja I, Seiwerth S, Sikiric P (2010) Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat