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More than three-quarters of patients taking both drugs reported at least one side effect, mostly mild to moderate gastrointestinal issues such as nausea, constipation, diarrhea and vomiting

When should I see a doctor about diarrhoea whilst taking B12

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Fendrick's employer, the University of Michigan, indeed does that

GIP agonism enhances the central incretin and anorectic effects of GLP-1, while reducing the incidence of nausea (Table 2).1,3,5 The effect on the GLP-1 receptor is biased due to the structure of TZP, which leads to reduced recruitment of beta-arrestin-1,42 thereby contributing to greater potency of the biological effect