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This dose increased oxidative stress, disrupted lipid metabolism, and suppressed ATP production

Neuroprotective agents for diabetic neuropathy Insulin and its analogues play a dual role in diabetic neuropathy management by regulating blood glucose and protecting nerve health, as hyperglycaemia-driven oxidative stress and inflammation are central to disease progression

A healthier liver improves digestion, reduces bloating, and promotes overall metabolic balance, which is essential for weight management

Although the CR group exhibited significantly lower lumbar spine and hip BMD compared to controls, there were no significant differences in serum CTX, bone-specific alkaline phosphatase (BSAP) levels, or trabecular microarchitecture parameters (e.g., erosion index, surface-to-volume ratio) between the groups

Extreme restriction is unnecessary and often counterproductive, causing metabolic slowdown that persists beyond the protocol