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Who should avoid glutathione

This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure

Ace 125 mg remains preferable to NSAIDs in patients with hepatic impairment and ascites (where NSAIDs cause significant renal risks), but must be dose-adjusted

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For example, if you are adding mushrooms rich in glutathione, like Reishi or Chaga, start with small amounts mixed into your dog's regular meals (or a high-quality supplement) and observe your dog to see how their body reacts