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In summary, while systemic IV DFO is invasive and non-specific for brain delivery for chronic brain iron overload, it may have potential applications for immediate effect and is useful in acute neurological damage where iron is rapidly released and accessible (e.g., acute iron poisoning or ICH)

Gene (2004) 343:1122.10.1016/j.gene.2004.08.021 13 AitkenRJRomanSD

Environ Microbiol 18(3):923935 Yang QY, Diao JW, Legrand NNG, Serwah BNA, Zhu M, Pang B, Zhang HY (2020) The protein expression profile and transcriptome characterization of Pichia caribbica induced by ascorbic acid under the oxidative stress

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