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It has generated real scientific interest from researchers in orthopedic medicine, gastroenterology, and longevity science

The HFI series of compounds, e.g., 37 (HFI 419) identified in 2008 after the virtual screening are much more drug-like than the hexapeptides 11 (AL-11), 12 (IVDE77), and the potent macrocyclic Ang IV analogue 23 (HA08) and can hopefully after further systematic optimization be converted into bioactive small molecules with capacity to cross the blood-brain barrier

Neurosci Res Commun

During the early 1980s Mojsov and Merrifield published a technique to obtain and crystallise pure synthetic glucagon

W., Muthupillai, R., Jahoor, F., Minard, C