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VEGFA secreted from cancer cells binds to VEGFR2 on endothelial cells, phosphorylates and activates VEGFR2, which then phosphorylates downstream extracellular signal-regulated kinase (ERK1/2) thus promoting angiogenesis (Ferracini et al., in vivo tumor angiogenesis by inhibiting VEGFA production through HGF/c-Met axis in HCC cells

ACS Med Chem Lett

This episode was produced by Rachel Carlson

These findings position curcumin as a promising candidate for diabetes treatment

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