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A meta-analysis of randomized controlled trials found systolic blood pressure reductions of 4.20 mmHg at 5 mg, 5.34 mmHg at 10 mg, and 5.77 mmHg at 15 mg

K., GLP-1RAs in type 2 diabetes: Mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data, Dec

Impact on NAION A paper published in 2024 in JAMA Ophthalmology created shock waves in the ophthalmic community by showing that subcutaneous semaglutide was associated with a significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy (NAION)

7 This is up from 40% among patients who started in 2023