One way it may do this is by reducing oxidative stress
Most medical documents indicate you might experience any of these: Mild diarrhea and/or upset stomach Difficulty breathing or swallowing Weight loss or weight gain Nervousness or restlessness Nausea or vomiting Headaches or migraines Paresthesias (tingling sensations) Rhinitis (chronic sneezing or a congested, drippy nose) Skin reactions, such as rash, itching, swelling, blisters, or pain at the site of injection Light joint pain Lightheadedness or dizziness Chest pain or discomfort Low blood potassium levels Irregular heartbeat Chills, night sweats, fever, or hot flushes General feeling of sickness However, people often fail to recognize that many side effects of vitamin B12 injections are consistent with B12 deficiency itself
Patients may need to meet certain requirements, such as proving the medication is medically necessary or showing that other treatments didnt work (step therapy)
Saffron and Sleep Quality: A Systematic Review of Randomized Controlled Trials
A systematic review published in 2025 identified 544 total articles on BPC-157 published between 1993 and 2024, filtering to 36 studies meeting inclusion criteria