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Annualized changes were compared between groups using analysis of covariance (ANCOVA) with adjustment for baseline clock value, chronological age, sex, BMI, high-sensitivity C-reactive protein (hsCRP), and soluble cluster of differentiation 163 (sCD163)

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Cooper shares clinical insights and explains why simple fixesstrict diets, calorie counting, and food restrictioncan actually backfire, causing more harm than good

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