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However, folate supplementation can mask these haematological changes whilst neurological damage continues, highlighting the importance of checking B12 status before commencing folate therapy

Methodologically, this layer can be interrogated by integrating hormone-response transcriptional programs, proteomic evidence of downstream effectors, and tissue or uterine-fluid metabolomic signatures capturing steroid-linked transformations

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Sanjari M, Safi Z, Tahroodi KM

3 Iron chelation for brain iron accumulation 3.1 FDA-approved iron chelators Current treatment of brain iron overload focuses on reducing iron levels and oxidative stress