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Because long-term safety data is limited for many emerging peptide uses, medical supervision is important

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Zlokovic, B

Direct effects of prolonged TNF- and IL-6 exposure on neural activity in human iPSC-derived neuron-astrocyte co-cultures

DHHC family protein acyltransferases (PATs) transfer palmitoyl groups to specific cysteine residues on substrate proteins [21, 22]

Systemic and local levels of these pro-inflammatory metabolitesincluding LPS, peptidoglycan and fatty acidsare elevated and cause damage in joint tissues by bringing about metabolic endotoxaemia, macrophage invasion and chronic low-grade inflammation (Han et al., 2025