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After 30 days of RYBELSUS treatment (after the initiation phase) [see Dosage and Administration (2.3)], patients may switch between RYBELSUS formulations (see Table 1)

HSD17B13, hydroxysteroid 17-beta dehydrogenase 13

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A vast number of preclinical and clinical studies have provided evidence for the potential role of GLP-1R agonists in modulating reward-seeking of food, alcohol, cocaine, and amphetamine, offering the possibility of a novel therapeutic alternative for treating addiction [112]