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Besides contributing to the increase of tumour mass, the rewiring of cholesterol and sphingolipids metabolism alters the composition of lipid rafts that play an important role in other hallmarks of cancer such as oncogenic signalling, migration, proliferation, adhesion, invasiveness, metastatic spread, apoptosis evasion [51], vesicular trafficking and drug resistance [52]

In addition to its weight loss benefits, AOD 9604 has been shown to enhance metabolic function, making it easier to maintain a healthy weight over the long term

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produced to research-grade purity

Signal Transduct Target Ther 2023, 8: 359