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The results have been consistently promising across multiple tissue types and organ systems, though large-scale human clinical trials remain limited

The data were released through a Lilly press announcement on May 21, 2026

From validated insulated shippers that maintain refrigerated ranges to advanced direct-to-patient delivery systems, ThermoSafe ensures medicines arrive potent, safe, and compliant with FDA expectations

We thank Daniel Drucker and Anthony Gramolini (Toronto, Canada) and Gary Lopaschuk (Edmonton, Canada) for helpful discussions and Daniel Drucker for providing the Glp1r / mice

38 GLP-1RAs increase microvascular blood flow in muscle tissue, enhance myocyte metabolism, inhibit muscle atrophy, and improve muscle mass and function