10.1166/jbn.2022.3248 48 ZhaoH.ShanY.MaZ.YuM.GongB
Tissue Maintenance, Aging, and Longevity-Oriented Research Because IGF-1 signaling is central to cell maintenance and repair, IGF-1 LR3 is also of interest in aging-related studies: Lifespan Correlations: Research in animal models (including mice, cows, and pigs) has explored correlations between IGF-1 levels, tissue integrity, and functional decline, using IGF-1 LR3 or similar constructs as tools to manipulate signaling
Li S, Zheng L, Zhang J, Liu X, Wu Z
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Further, the biosynthesis of Sec on tRNA [ser]Sec starts with the loading of a serine residue on tRNA [ser]Sec followed by its phosphorylation through the enzyme O-phosphoseryl-tRNA [Ser]Sec kinase (PSTK) to form phosphoseryl-tRNA [Ser]Sec