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PloS One (2017) 12(2):e0171293

Purines and pyrimidines play an important role in DNA and RNA synthesis, which is required for high-rate cancer cell proliferation

Microbiome differences were greater between the two groups switched from WD to LD (i.e., WD/LD-V and WD/LD-T) and the two diet control groups (i.e., LD/LD-V and WD/WD-V) compared to the microbiome differences observed between the lean (LD/LD-V) and obese (WD/WD-V) control groups