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In populations of adults with overweight or obesity, use of tirzepatide was associated with significantly greater weight loss than semaglutide [26] [27], suggesting that the superior efficacy observed in controlled trials translates to clinical practice
Skin flap necrosis and poor wound healing may also occur, especially in patients with compromised vascularity or ongoing weight fluctuations, he noted
But that health improvement comes at a high cost
Heart sections stained with 2,3,5-triphenyltetrazolium chloride (TTC) harvested 4 days after MI revealed obvious reductions in unstained infarct areas of GLP-1(2836)treated hearts as compared with the scramble- or saline-treated controls (Figure 1B)
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