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They may be appropriate for: Severe metabolic dysfunction Advanced insulin resistance Short-term metabolic stabilization with supervision Caution is warranted for those with: Chronic gut dysfunction Leaky gut Thyroid disorders Hormonal imbalance History of under-eating or disordered eating Low muscle mass In these cases, appetite suppression can worsen existing dysfunction

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Further studies are needed to understand the effect of GLP-1RAs in other ethnic populations

Appetite suppression, weight loss, and blood sugar improvement do not arrive at the same time

Monitoring your diet and digestion rate can help discern the cause