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GLP-1 Receptors and Skin Inflammation Beyond the indirect effects of weight loss, GLP-1 receptors are present in skin tissue, including in keratinocytes, the primary cells of the outer skin layer, and in immune cells resident in skin

The underlying mechanism generally consists of the oxidation of redox-reacting cysteine and/or tyrosine residues located within or near the active site, which creates intraprotein and interprotein bridges that affect protein function 8,9

Anti-inflammatory activity Garlic-derived organosulfur compounds have been found to inhibit mediators of the inflammatory response, including cytokines, chemokines, adhesion molecules, and enzymes like cyclooxygenase (COX), lipoxygenase (LOX), and inducible nitric oxide synthase (iNOS) (34-36)

Endogenously, free radicals are by-products of normal cellular metabolism (Fig