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Other indications include malabsorption disorders (such as Crohn's disease or coeliac disease), following gastric surgery, strict vegan diets without supplementation, and certain medications that interfere with B12 absorption

Because many degradation pathwaysincluding hydrolysisrequire the presence of water, freeze-dried peptides generally remain stable much longer than their reconstituted counterparts when stored under appropriate laboratory conditions

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Nerve: 300 to 500 mcg once or twice daily, subcutaneous, 8 to 12 weeks

However, cycling prevents potential receptor desensitization, allows natural healing integration, reflects a conservative approach given limited long-term human data, and reduces cost