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356,357 The activated AMPK pathway can upregulate the expression of FTH1 and GPX4 in intestinal tissues and can improve iron metabolism and redox disorders in the colons of UC rats, thereby effectively treating UC

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A 2008 study in The FASEB Journal (Atamna et al.) found that low doses (0.54 mg/kg) in animals and humans stimulated mitochondrial function for enhanced cellular energy was well-tolerated