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In 58.8% (10/17) of patients, NIRS data were improved and ammonia levels were decreased, whereas 23.5% (4/17) of patients showed improved NIRS data without decreasing serum ammonia levels at 8 weeks

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While ADHD is associated with abnormal levels of both dopamine and serotonin metabolites, it is possible that deviations in serotonin activity play a role in specific subgroups of ADHD, contributing to impulsive behavior and externalizing or cognitive impulsivity

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