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Potential risks and contraindications Given the limited understanding of DSIPs mechanisms and effects in humans, certain risks and contraindications must be taken into consideration: Unknown long-term effects : The long-term safety of DSIP has not been well-established, and the potential risks associated with chronic use remain unclear

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References Johan F B Arendt, Ebba Nexo

134136 Clinical studies have reported that compared with healthy controls, plasma, CSF, and saliva TMAO levels in PD patients are significantly elevated

doi: 10.1186/s12864-020-6511-6 111 Gonzlez-MariscalL.Raya-SandinoA.Gonzlez-GonzlezL.Hernndez-GuzmnC