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Its origin is multifactorial and appears related to immature liver enzyme systems (such as glucuronyl transferase ), a higher turnover of red cells (incorporating the transition from fetal to adult haemoglobin) and, occasionally, to the effects of breastfeeding
This figure provides an overview of the key steps, including the creation of mutant mice, breeding, GH treatment, blood sample collection, untargeted metabolomic analysis, data processing, and the subsequent discovery of biomarkers
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