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Aizawa S, Ookawa K, Kudo T, Asano J, Hayakari M, Tsuchida S

Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+

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Copper peptides support barrier function rather than disrupting it, making them potentially gentler than many other active ingredients

Rarely, users report headaches, fatigue, or digestive upset