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Xu et al., 2017) signaling pathways (including by activation of pro-apoptotic caspase3, down-regulation of the anti-apoptotic proteins XIAP, survivin, and p-Akt, improved Bax/Bcl-2 ratio leading to cytochrome c release, increased GRP78, GRP94, phosphorylated protein kinase R-like ER kinase and phosphorylated eukaryotic initiation factor 2), and inhibition of G 1 -S cell cycle progression (Wong et al., 2022)

Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB

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While Adderall is a wake-promoting agent, its effects are highly dose-dependent

Q.LiC.et al (2025)