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Inhibition of NO-synthase (NOS) that causes decrease in local NO production, impaires gastric microcirculation and aggravates gastric lesions induced by noxious agents (12,13)

Moreover, the expression of key spermatogenesis markers, including UCHL1, PLZF, SCP3, and PCNA, which were reduced in aged testes, were significantly restored or increased following FOXO4-DRI treatment

ProtocolGuinea Pig Female albino guinea pigs rats (n=6 per group) of approximately 6-8 weeks of age served as subjects for the experiments

Allergy, 53, 115-120

The SAR study by the modification of substituent revealed that optimum bulkiness at meta positions of the benzyl ring can also improve the inhibition potential of compounds