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They can also improve cognitive function, helping you think clearly, focus better, and feel more at ease

[10] [11] While the primary therapeutic effect targets glucose regulation, the presence of these receptors in regions associated with mood and cognition raises theoretical questions about broader effects, though human evidence for direct personality changes is lacking

Both medications use gradual dose increases to reduce side effects

But there are signs that stigma is starting to break down

TPP functions as a cofactor for several critical enzymes across three metabolic pathways: transketolase (TK) in the pentose phosphate pathway, pyruvate dehydrogenase (PDH) in glycolysis, and alpha-ketoglutarate dehydrogenase (AKD) in the Krebs cycle (33, 34)